Biomarker may predict early Alzheimer's disease

Medical Xpress| Fri Nov 10 01:19:13 EST 2017
Researchers at Sanford Burnham Prebys Medical Discovery Institute (SBP) have identified a peptide that could lead to the early detection of Alzheimer's disease (AD). The discovery, published in Nature Communications, may also provide a means of homing drugs to diseased areas of the brain to treat AD, Parkinson's disease, as well as glioblastoma, brain injuries and stroke. "Our goal was to find a new biomarker for AD," says Aman Mann, Ph.D., research assistant professor at SBP who shares the lead authorship of the study with Pablo Scodeller, Ph.D., a postdoctoral researcher at SBP. "We have identified a peptide (DAG) that recognizes a protein that is elevated in the brain blood vessels of AD ..

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